Frequently Asked Questions (FAQ) about Dr. Matthew #1 Digestive Enzymes


1. Why do We Need These Enzymes and What are the Benefits of Taking them?
Find answer here.

2. What is Unique about this Digestive Enzyme Supplement?
This is the only supplement in the market that contains 19 digestive enzymes in these specific amounts. Most digestive enzyme formulas contain only 5-8 enzymes, and in lower amounts. But this unique formulation is the most complete (full spectrum) available today.

Why is it important that a digestive enzyme supplement contains the full spectrum of necessary digestive enzymes? Because our body requires all these enzymes in order to break down and absorb the nutrients in the food we eat. Each food group we ingest can be broken down only by a specific enzyme. The major food groups are Proteins, Carbohydrates, and Fats. Proteins are broken down by proteases, carbohydrates are broken down by amylases, and fats are broken down by lipases. But there are many other enzymes that our body needs in order to digest specific nutrients that we ingest daily.For example, we need lactase to digest lactose—a disaccharide found in dairy products. It is estimated that 75% of adults worldwide have decreased lactase activity. They are lactose intolerant. As a result,  lactose is not digested, and this causes bloating, diarrhea, and gas.

Our body needs enzymes to digest gluten—a protein present in wheat, barley, rye, and oat. Undigested gluten causes fatigue, gas, and abdominal pain to people who have gluten sensitivity. Dr. Matthew #1 Digestive Enzymes contain Aspergillopepsin and Dipeptidyl peptidase IV. Studies have proven that these two enzymes break down gluten. Research suggests that these two enzymes may soothe conditions that cause gluten intolerance.

We are all familiar with the usual gassy discomfort after eating beans and certain greens (broccoli, cabbage, and cauliflower). This is because these foods contain glycolipids and glucoproteins that our stomach cannot easily digest. Dr. Matthew #1 Digestive enzymes contain alpha-Galactosidase, an enzyme that effectively breaks down these nutrients thereby reducing bloating, discomfort, and flatulence.

When we eat greens and vegetables, we take in large amounts of plant cells. Plant cells are difficult to digest because they are surrounded by a complex fibrous structure called “cell wall”. Dr. Matthew Digestive Enzymes contain Xylanase, Hemicellulase, Pectinase, and Cellulase that break down the hard-to-digest plant fibers that compose the cell wall. This action not only liberates important plant nutrients [1, 2, 3, 4] that were trapped within the plant walls and that our body can now easily absorb, it reduces the gas and intestinal discomfort that this undigested material causes.

The majority of digestive enzyme products currently in the market do  not contain these important enzymes.

3. What Enzymes does this Product Contain?
Each one of these 18 enzymes breaks down a specific food group. Read this article to see in more detail what food group each enzyme targets.

4. When should I take #1 Digestive Enzymes and how much?
Take 1 or 2 capsules right before your meal (before your first bite). There is no harm in taking one later, it just may not assist your digestion that much.

5. I tried these enzymes and didn’t see any effect on my digestion. What should I do?
The main reason people report little success with digestive enzymes is simply because they are under dosing. Therefore, if you don’t see the desired effect with one capsule, take two.

6. Should I take this product only before a meal or can I take it also before drinking a protein shake, eating a piece of cake, or any other food?
You should take these enzymes to facilitate digestion of any food that upsets your digestion.

7. Can it Help Me Digest gluten?
Absolutely. It contains two enzymes that specifically cleave gluten: Aspergillopepsin and Dipeptidyl-Peptidase 4 (DPP-IV). In vitro studies have shown that DPP-IV efficiently degrades the immunodominant, proline-containing epitope of gliadin, the primary allergenic protein in gluten. A growing body of scientific evidence suggests that supplementation with DPP-IV can substantially improve the digestive and neurobehavioral symptoms associated with reactivity to gluten, casein, and other allergenic and neuroactive dietary proteins.

8. I have Celiac Disease, Can this supplement help me digest gluten completely?
No. While this supplement contains the enzymes Aspergillopepsin (ASP) and Dipeptidyl-Peptidase 4 (DPP-IV) which digest gluten, it does not necessarily completely digest the particular amino acid sequence on gluten that is responsible for celiac disease. If you have celiac disease you must avoid even trace amounts of gluten. So far, research has established that no digestive supplement can completely degrade the amino acid chain in gluten that causes celiac disease symptoms. However, clinical studies are ongoing to evaluate if “a fixed dose ratio combination of ASP and DPPIV can provide near-term relief for celiac patients suffering from inadvertent gluten exposure“. In addition to ASP and DPP-IV, Dr. Matthew #1 Digestive Enzymes contain other proteolytic enzymes, including papain, which have been clinically shown to be effective in some cases of gluten allergy. In at least one case study, a celiac patient who received oral papain began to tolerate some gluten and experienced better absorption and stool formation.

9. Is this chewable?
No. It’s an easy to swallow capsule.

10. If the pills are too big for me to swallow, can I open them in a glass of juice or water?
Yes, you can.

11. How long is the capsule?
It’s 0.75 inch long.

12. Is this product suitable for vegetarians?
Yes, it is. Some of the enzymes in this formulation are sourced from plants while others from naturally occurring microorganisms (like Aspergillus oryzae) that are completely harmless to humans. There are no animal-based enzymes in this product.

13. Is it suitable for Vegans?
Yes, it is. It is formulated to exclude animal products (dairy, fish)

14. Is it Gluten-Free?
Yes, it is. According to the FDA’s definition of “gluten-free”, foods can be labeled gluten-free if the concentration of gluten in that food is no more than 20ppm (parts per million). A third party laboratory tests each batch of our product for gluten. The concentration of gluten in Dr. Matthew #1 Digestive enzymes is lower than 20ppm, and therefore it meets FDA’s definition of “gluten-free”.

15. I have a problem digesting dairy, wheat, and soy.
Yes, if you have food intolerance toward dairy, wheat or soy—that means, you have difficulty digesting these foods—this product was made for you. It has specific enzymes that effectively break down dairy, wheat and soy.

16. What is the best place to store it? Should I keep the enzymes in the refrigerator?
No, you can keep that at room temperature (70 degrees) in your pantry, in the same place you keep your multivitamins, away from a heat source, and also away from moisture. Storing in the refrigerator will not hurt except for the moisture.

17. Will this product reduce the enzymes that my body produces? My herbal specialist has told me NOT to take digestive enzymes… guess I need to ask why she said that.
I have no idea why she’d say that…If this theory was true, then we shouldn’t eat raw foods because they’re full of enzymes and could possibly reduce the natural enzymes our body produces. But we know this is not how it works.

Sometimes theories are not based on science but on fear. What may happen when you take digestive enzymes is that your body will re-allocate resources to other places and allow your systems to function more efficiently.

18. Are the capsules enteric coated or acid resistant?
No, they don’t need to be. Vegetarian enzymes retain their activity in the acidic environment of the stomach. Laboratory studies have proven that vegetarian (fungal) enzymes not only survive the acidity of the stomach but are also active in that harsh environment. It’s the animal (pancreatic) enzymes that have to be “enteric coated” to be protected from acidity of the stomach so that they can be shuttled to the duodenum where digestion continues.

19. Does it have a Laxative effect?

20. Digestive enzymes contain amylase which breaks down starch. This speeds up the absorption of glucose. Won’t this accelerate the glycemic response making the body’s response to starches unhealthy?
No, studies have found the exact opposite. Following starch ingestion, people with high amylase activity had better glycemic homeostasis (lower blood glucose concentration) than people with low amylase activity. Therefore, taking digestive enzymes with amylase may lower your diabetic risk.

21. Can it Help Reduce Indigestion and Heartburn?
If you experience indigestion or heartburn, talk to your doctor because these might be symptoms of a serious medical problem like heart attack, gallbladder disease or ulcer. If you heartburn is caused by acid reflux (GERD), this product may help (see below).

22. Can it Help GERD (Gastroesophageal Reflux Disease)?
Yes and No. Acid reflux occurs when the valve that separates the stomach from the esophagus fails to remain closed when it should. As a result, the gastric content escapes the stomach and travels upwards causing irritation of the lining of the esophagus, and heartburn. Normally, after the food stays in the stomach for a while, it should move to the intestinal tract. In some people, the food stays in the stomach longer than it should. They have an abnormally long gastric transit time. This delayed stomach emptying increases the likelihood of a reflux event. Digestive enzymes can accelerate stomach emptying thereby lowering the possibility of backwash of acidic stomach contents towards the lower part of the esophagus. Dr. Leo Galland, MD, author at Huffington Post, and internationally recognized as a leader in integrated medicine, has found that digestive enzymes can help many people reduce acid reflux because they decrease distension of the stomach. The enzymes should be acid-resistant (like Dr Matthew #1 Digestive Enzymes), so they work in the stomach itself (not in the small intestine), decreasing gastric transit time. On the flip side, if a person takes digestive enzymes and a reflux event occurs, digestive enzymes may further irritate the esophageal lining. Talk with your doctor before using digestive enzymes if you experience acid reflux. If you are on medication for acid reflux, keep taking what your doctor prescribed for you. However, keep in mind that there are also natural options that you can discuss with your doctor.

23. Why is Dr. Matthew #1 Digestive Enzymes Supplement better than Acid-Lowering drugs at Alleviating Heartburn?
The stomach produces hydrochloric acid to help digestion of proteins and also kill bacteria that enter the stomach. When the food stays in the stomach for too long, due to insufficient production of enzymes, the risk for esophageal reflux increases. It’s the acidity of the gastric content that causes heartburn in the esophagus. Acid-lowering drugs reduce the acidity but they don’t treat the root of the problem (poor enzyme production). Thus, the reflux often remains. The irony of treating people with GERD by making gastric juices less acidic is that food doesn’t digest as well, which can be a contributing factor to GERD. What’s worse, these drugs produce serious—and well documented in medical journals side effects—including increased risk for intestinal infection and increased risk of hip fractures. Decreasing the acidity of your stomach acid may provide short term relief, but it’s not a long term solution. Dr Matthew #1 Digestive Enzymes, on the other hand, reduce the risk for a reflux event because they facilitate and accelerate stomach emptying, that is, the digestion of otherwise undigested food in the stomach.

24. I am a healthy individual above 50. Why should I take digestive enzymes?
After about age 50, the pancreas produces only about half the amount of digestive enzymes that it did when you were younger. As a result, the food you eat is not broken down efficiently. It reaches the colon still undigested leading to noxious gas, bloating, cramping, and other digestive problems. This can lead to chronic malnutrition and stomach distress after most meals. Over-the-counter drugs like Alka-Seltzer® and Pepto-Bismol® can provide temporary relief, but they don’t treat the underlying cause of the problem. Dr. Matthew #1 digestive enzymes address the root of the problem: they provide your body with the digestive enzymes it needs to fully break down and assimilate the nutrients you ingest.

25. I am younger than 50 and as healthy as can be. Why should I take digestive enzymes?
Do you eat grains, nuts, legumes or cruciferous vegetables (i.e cabbage, broccoli)? What about foods that contain dairy or fiber? Do you occasionally eat a big meal, like the annual Thanksgiving overindulgence? Do you sometimes consume more than your fair share of high-fat foods, like avocados, whole eggs, olives, dark chocolate, cheese or beef—all of which contribute to what is known as slow stomach emptying? Do you occasionally indulge in junk food, like pizza and hamburgers or a meal loaded with carbs? In all these cases, one of the following two (or both) occurs:

– a significant part of the food you eat leaves your stomach undigested. Undigested food begins to rot and ferment in the intestines and colon, feeding bacteria which create flatulence (methane and hydrogen sulfide gases) as a byproduct.

– your digestive system becomes overloaded with the breakdown of all these nutrients, particularly the excessive fat and carbs. An overly stressed digestive system results in poor nutrient absorption, sleep disruption, and fatigue.

Dr. Matthew #1 Digestive Enzymes promote a healthy digestion. They help you digest even those hard-to digest foods. They prevent intestinal gas and abdominal discomfort in all cases mentioned above. This unique enzyme blend promotes digestive health, optimizes nutrient absorption, and ultimately leads to better sleep, and more energy and vitality.

26. It Contains Hypromellose. I have read that it’s not good. Are These Enzymes Safe?

The Internet is full of misinformation, especially in matters that relate to health, as many people like posting their views on subjects they are not experts at.

Dr. Matthew #1 Digestive Enzymes contain 19 natural enzymes that exist naturally in plants and our very own body. They are 100% free of GMO, colors and artificial flavors. They are also manufactured to exclude all common allergens.

The enzymes  in Dr. Matthew’s formulation are enclosed in a vegetable capsule which is made of Hypromellose and Water.

Hypromellose is 100% safe. It’s a substance that is derived from plant cellulose. Hypromellose is approved by the FDA.

A number of scientific studies have confirmed the safety of Hypromellose. Here is one:

Disclaimer: * These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. The content in this website is based on the opinions of Dr. Matthew, unless otherwise noted. The information on this website should by no means replace a one-on-one relationship with a qualified health care professional. It is certainly not intended as medical advice. It is intended as a sharing of knowledge and information from the research of Dr. Matthew and his partners. If you are pregnant, nursing, taking medication, or have a medical condition, consult your physician before using products based on this content.